One of the speakers of the event, moderated by Prof. Carla Bruschelli, was Prof. Riccardo Polosa, founder of CoEHAR, Center of Excellence for the acceleration of Harm Reduction, and professor of Internal Medicine at the University of Catania. The subject of his speech was the patient with COPD (Chronic Obstructive Pulmonary Disease) with addiction to smoking, which he defined as "a difficult patient, because he has a long history that has created a strong alliance with cigarettes. Therefore, giving up smoking leads him to a great form of distress, because it represents a loss”.