The main goal of the Conference is to introduce the current status of New Alternative Methods and their potential to support Tobacco Harm Reduction worldwide. The aim of the CORESTA conference is also to foster scientific engagement between CORESTA members and THR international community to facilitate the discussion around reduced risk devices and support evidence-based tobacco regulatory policies.

CORESTA (Cooperation Centre for Scientific Research Relative to Tobacco) is an association aimed to promote international cooperation in scientific research relative to tobacco and its derived products. 

The event will be held online from Monday, 18 October 2021 until Thursday, 28 October 2021. 

The topics discussed will span from analysing the Advancing New Alternative Methods (NAMs) for Tobacco Harm Reduction, to evaluating methods for in vitro and in vivo toxicology in pre-clinical toxicology.

The main goal of the Conference is to introduce the current status of New Alternative Methods and their potential to support Tobacco Harm Reduction worldwide. The aim of the CORESTA conference is also to foster scientific engagement between CORESTA members and THR international community to facilitate the discussion around reduced risk devices and support evidence-based tobacco regulatory policies.

Massimo Caruso

Among the panellist, Prof. Massimo Caruso, which speech centred on the paper – led by Caruso and researcher Lia Emma – “What is the best approach to assess the vapour-induced cytotoxicity of ENDS? A road map going to the destination.” 

The study, delivered by the Center of Excellence for the Acceleration of Harm Reduction (CoEHAR) of the University of Catania, focused on asses and screening different in vitro cytotoxicity methods for the assessment of ENDS toxicity.

Among the result of the research, all tests showed reduced cell viability following smoke exposure while slight or no reduction with all the ENDS. Furthermore, CoEHAR’s researchers conclude that ENDS induce hugely reduced damage to cell viability on epithelial bronchial cells compared to tobacco cigarettes.

The paper also pinpoints the need for a comprehensive and shared international approach on cytotoxicity studies as a fundamental step in assessing the potential ENDS toxicity.

The Center of Excellence for the Acceleration of Harm Reduction (CoEHAR) has been on the frontline in setting shared methodology among the international scientific community for the studies on e-cigarettes. In particular, for the likely health outcomes of the regular uses of these devices.  

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